DEEP MUTATIONAL SCAN OF ALL POSSIBLE HNF1A MISSENSE VARIANTS

This lookup table provides functional interpretation of any missense variant in HNF1A based on the deep mutation scan of HNF1A conducted in human hepatocytes. For each queried missense variant, the function score and the posterior error probability of the variant being WT-like instead of function altering are returned (see help for more information). The queried variant is visualized relative to all tested missense variants and to the included synonymous HNF1A variants.

Examples - Protein change: p.L12H or p.Leu12His
Genomic coordinates in hg19: chr12:121416606-T-A